COVID-19 Critical Care Consortium:
A global collaboration born from a global crisis

Established in early 2020, the COVID-19 Critical Care Consortium (COVID Critical) is a global alliance of healthcare professionals and researchers committed to identifying the most effective treatments for critically ill COVID-19 patients.

At the beginning of the pandemic, there was a paucity of data that could be used to guide the management of critically ill patients with COVID-19. In response, COVID Critical, an international research and data-sharing collaborative, was assembled to harness the cumulative experience of intensive care units (ICUs) worldwide.

More than 400 hospitals and affiliated research facilities across 64 countries are contributing to COVID Critical’s world-first database to build an intensive care profile for a disease that was completely unknown before December 2019.

Proudly established and headquartered in Queensland, Australia, our mission is to equip all intensive care clinicians, regardless of nationality, affiliation or economic status, with the best and most up-to-date information to save lives and improve outcomes for patients with COVID-19.

A global alliance of over 400 hospitals in 64 countries, COVID Critical has created the world’s largest database of COVID-19 ICU patient information to support clinicians on the front line.

Are you a participating site? Click the link below to access important study documents.

COVID Critical research publications

Featured
Variability of oxygen requirements in critically ill COVID-19 patients

Samuel F Huth, Alexander Rothkopf, Lisa Smith, Nicole White, Gianluigi Li Bassi1, Jacky Y Suen, John F Fraser, COVID-19 Critical Care Consortium

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Epidemiology and outcomes of early-onset AKI in COVID-19-related ARDS in comparison with non-COVID-19-related ARDS: insights from two prospective global cohort studies

Bairbre A. McNicholas, Emanuele Rezoagli, Andrew J. Simpkin, Sankalp Khanna, Jacky Y. Suen, Pauline Yeung, Daniel Brodie, Gianluigi Li Bassi, Tai Pham, Giacomo Bellani, John F. Fraser & John Laffey on behalf of the CCCC Consortium

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Race and ethnicity in the COVID-19 Critical Care Consortium: demographics, treatments, and outcomes, an international observational registry study

Matthew J. Griffee, David A. Thomson, Jonathon Fanning, Dorothea Rosenberger, Adrian Barnett, Nicole M. White, Jacky Suen, John F. Fraser, Gianluigi Li Bassi & Sung-Min Cho On behalf of the COVID-19 Critical Care Consortium.

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Characteristics and outcomes of patients with severe COVID-19 in Indonesia: Lessons from the first wave

Erlina Burhan, Keibun Liu, Eva M. Marwali, Samuel Huth, Navy G. H. M. L. Wulung, Dafsah A. Juzar, Muhammad A. Taufik, Surya O. Wijaya, Dyah K. Wati, Neurinda P. Kusumastuti, Saptadi Yuliarto, Bhirowo Y. Pratomo, Erwin Pradian, Dadang H. Somasetia, Desy Rusmawatiningtyas, Arie Z. Fatoni, Jose M. Mandei, Eka Y. Lantang, Fajar Perdhana, Bambang P. Semedi, Muhammad Rayhan, Tiffany R. S. Tarigan, Nicole White, Gianluigi L. Bassi, Jacky Y. Suen, John F. Fraser.

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Iliopsoas Haematoma during Extracorporeal Membrane Oxygenation

Taniguchi H, Rätsep I, Heinsar S, Liu K, Cespedes M, Suen JY, Li Bassi G, Fraser JF, Jacobs JP, Peek GJ.

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Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study

LF Reyes, S Murthy, E Garcia-Gallo, Covid-19 Critical Care Consortium, ISARIC Clinical Characterisation Group, et al.

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Interleukin-6 inhibitors in non-COVID-19 ARDS: analyzing the past to step into the post-COVID-19 era

Gandini L, Fior G, Schibler A, Obonyo N.G, Li Bassi G, Suen JY, Fraser JF

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Cerebrovascular Complications of COVID-19 on Venovenous Extracorporeal Membrane Oxygenation

AM Zaaqoq, MJ Griffee, TL Kelly, JP Fanning, S Heinsar, JY Suen, Jacky, S Mariani, G Li Bassi, JP Jacobs, N White, JF Fraser, R Lorusso, GJ Peek, S Cho, COVID-19 Critical Care Consortium

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Morbid obesity’s impact on COVID-19 patients requiring venovenous extracorporeal membrane oxygenation: The covid-19 critical care consortium database review

Javidfar, J., Zaaqoq, A. M., Labib, A., Barnett, A. G., Hayanga, J. A., Eschun, G., Yamashita, M. H., Jacobs, J. P., Heinsar, S., Suen, J. Y., Fraser, J. F., Bassi, G. L., Arora, R. C., Peek, G. J., & Covid-19 Critical Care Consortium

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Hemorrhage, Disseminated Intravascular Coagulopathy, and Thrombosis Complications Among Critically Ill Patients with COVID-19

Fanning, Jonathon P., Weaver, Natasha, Fanning, Robert B., Griffee, Matthew J., Cho Sung-Min, Panigada, Mauro, Obonyo, Nchafatso G. Zaaqoq, Akram M.; Rando, Hannah; Chia, Yew Woon; Fan, Bingwen Eugene; Sela, Declan; Chiumello, Davide; Coppola, Silvia; Labib, Ahmed; Whitman, Glenn J. R.; Arora, Rakesh C.; Kim, Bo S.; Motos, Anna; Torres, Antoni; Barbé, Ferran; Grasselli, Giacomo; Zanella, Alberto; Etchill, Eric; Usman, Asad Ali MMD, MPH30; Feth, Maximilian; White, Nicole M.; Suen, Jacky Y.; Li Bassi, Gianluigi; Peek, Giles J.; Fraser, John F.; Dalton, Heidi on behalf of the COVID-19 Critical Care Consortium (COVID Critical)

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Transcriptomic profiling of cardiac tissues from SARS-CoV-2 patients identifies DNA damage

A Kulasinghe, N Liu, C W Tan, J Monkman, J E Sinclair, D D Bhuva, D Godbolt, L Pan, A Nam, H Sadeghirad, K Sato, G L Bassi, K O'Byrne, C Hartmann, A F R dos Santos Miggiolaro, G L Marques, L Z Moura, D Richard, M Adams, L de Noronha, C Pellegrino Baena, J Y Suen, R Arora, G T Belz, K R Short, M J Davis, F Souza-Fonseca Guimaraes, J F Fraser.

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Neurological manifestations of COVID-19 in adults and children

Sung Min Cho, Nicole White, Lavienraj Premraj, Denise Battaglini, Jonathon Fanning, Jacky Suen, Gianluigi Li Bassi, John Fraser, Chiara Robba, Matthew Griffee, Bhagteshwar Singh, Barbara Wanjiru Citarella, Laura Merson, Tom Solomon, David Thomson, the ISARIC Clinical Characterisation Group.

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ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

ISARIC Clinical Characterization Group, Esteban Garcia-Gallo, Laura Merson, Kalynn Kennon, Sadie Kelly, Barbara Wanjiru Citarella, Daniel Vidali Fryer, Sally Shrapnel, James Lee, Sara Duque, Yuli V. Fuentes, Valeria Balan, Sue Smith, Jia Wei, Bronner P. Gonçalves, Clark D. Russell, Louise Sigfrid, Andrew Dagens, Piero L. Olliaro, Joaquin Baruch, Christiana Kartsonaki, Jake Dunning, Amanda Rojek, Aasiyah Rashan, Abi Beane, Srinivas Murthy & Luis Felipe Reyes

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Tracheostomy outcomes in critically ill COVID-19 patients: a systematic review, meta-analysis, and meta-regression

Denise Battaglini, Lavienraj Premraj, Nicole White, Anna-Liisa Sutt, Chiara Robba, Sung-Min Cho, Ida Di Giacinto, Filippo Bressan, Massimiliano Sorbello, Brian Cuthbertson, Gianluigi Li Bassi, Jacky Suen, John Fraser, Paolo Pelosi.

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COV3: The Impact of Morbid Obesity on Patients with COVID-19 who Develop Respiratory Failure requiring Extracorporeal Membrane Oxygenation

Javidfar, Jeffrey; Zaaqoq, Akram M.; Barnett, Adrian; Labib, Ahmed; Arora, Rakesh; Hayanga, J. W. Awori; Eschun, Greg; Yamashita, Michael; Jacobs, Jeffrey; Heinsar, Silver; Suen, Jacky; Fraser, John; Bassi, Gianluigi Li; Peek, Giles.

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Neurological Manifestations of SARS-CoV-2 Infection: Protocol for a Sub-analysis of the COVID-19 Critical Care Consortium Observational Study

Denise Battaglini, Lavienraj Premra, Matthew Griffee, Samuel Huth, Jonathon Fanning, Glenn Whitman, Diego Bastos Porto, Rakesh Arora, Lucian Durham, Eric Gnall, Marcelo Amato, Virginie Williams, Alexandre Noel, Sabrina Araujo De Franca, Gordan Samoukovic, Bambang Pujo, David Kent, Eva Marwali, Abdulrahman Al-Fares, Stephanie-Susanne Stecher, Mauro Panigada, Marco Giani24,25, Giuseppe Foti, Paolo Pelosi, Antonio Pesenti, Nicole Marie White, Gianluigi Li Bassi, Jacky Suen, John F. Fraser, Chiara Robba, Sung-Min Cho and the COVID-19 Critical Care Consortium

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Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS

Li Bassi G, Gibbons K, Suen JY, Dalton HJ, White N, Corley A, Shrapnel S, Hinton S, Forsyth S, Laffey JG, Fan E, Fanning JP, Panigada M, Bartlett R, Brodie D, Burrell A, Chiumello D, Elhazmi A, Esperatti M, Grasselli G, Hodgson C, Ichiba S, Luna C, Marwali E, Merson L, Murthy S, Nichol A, Ogino M, Pelosi P, Torres A, Ng PY, Fraser JF; COVID-19 Critical Care Consortium.

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Venovenous extracorporeal membrane oxygenation in patients with acute covid-19 associated respiratory failure

Urner M, Barnett AG, Bassi GL, Brodie D, Dalton HJ, Ferguson ND, Heinsar S, Hodgson CL, Peek G, Shekar K, Suen JY, Fraser JF, Fan E; COVID-19 Critical Care Consortium

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Non-Invasive Multimodal Neuromonitoring in Non-Critically Ill Hospitalized Adult Patients With COVID-19

Battaglini D, Premraj L, Huth S, Fanning J, Whitman G, Arora RC, Bellapart J, Bastos Porto D, Taccone FS, Suen JY, Li Bassi G, Fraser JF, Badenes R, Cho SM, Robba C; COVID-19 Critical Care Consortium.

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Impact of renin–angiotensin–aldosterone system inhibition on mortality in critically ill COVID-19 patients with pre-existing hypertension: A prospective cohort study

Kei Sato, Nicole White, Jonathon P. Fanning, Nchafatso Obonyo, Michael H. Yamashita, Vinesh Appadurai, Anna Ciullo, Meryta May, Elliott T. Worku, Leticia Helms, Shinichiro Ohshimo, Dafsah A. Juzar, Jacky Y. Suen, Gianluigi Li Bassi, John F. Fraser, Rakesh C. Arora on behalf of COVID-19 Critical Care Consortium Investigators

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Mid and long-term neurological and neuropsychiatric manifestations of post-COVID-19 syndrome: A meta-analysis

Lavienraj Premraj, Nivedha V. Kaanapali, Jack Briggs, Stella M. Seal, Denise Battaglini, Jonathon Fanning, Jacky Suen, Chiara Robb, John Fraser, Sung-Min Cho

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Beneficial Effect of Prone Positioning During Venovenous Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019

Zaaqoq, A. M., Barnett, A. G., Griffee, M. J., MacLaren, G., Jacobs, J. P., Heinsar, S., Suen, J. Y., Bassi, G. L., Fraser, J. F., Dalton, H. J., Peek, G. J., COVID-19 Critical Care Consortium

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Prone position during venovenous extracorporeal membrane oxygenation: survival analysis needed for a time-dependent intervention

Akram M. Zaaqoq, Adrian G. Barnett, Silver Heinsar, Matthew J. Griffee, Graeme MacLaren, Jeffrey P. Jacobs, Jacky Y. Suen, Gianluigi Li Bassi, John F. Fraser, Heidi J. Dalton, Giles J. Peek on behalf of the COVID-19 Critical Care Consortium

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Venovenous extracorporeal membrane oxygenation in obese patients

Javidfar, J., Zaaqoq, A. M., Yamashita, M. H., Eschun, G., Jacobs, J. P., Heinsar, S., Hayanga, J. W., Peek, G. J., & Arora, R. C. (2021). JTCVS techniques, 10, 335–348.

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Mobile Extracorporeal Membrane Oxygenation for Covid-19 Does Not Pose Extra Risk to Transport Team

Javidfar, J., Labib, A., Ragazzo, G., Kurtzman, E., Callahan, M., Heinsar, S., Gudzenko, V., Barrett, P., Binongo, J., Wei, J. W., Fraser, J., Suen, J. Y., Li Bassi, G., Peek, G., & Covid-19 Critical Care Consortium

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Ischemic and Hemorrhagic Stroke Among Critically Ill Patients With Coronavirus Disease 2019: An International Multicenter Coronavirus Disease 2019 Critical Care Consortium Study

Cho SM, Premraj L, Fanning J, Huth S, Barnett A, Whitman G, Arora RC, Battaglini D, Porto DB, Choi H, Suen J, Bassi GL, Fraser JF, Robba C, Griffee M.

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Assessment of 28-Day In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019: An International Cohort Study

Gianluigi Li Bassi, Jacky Suen, Nicole White, Heidi Dalton, Jonathon Fanning, Amanda Corley, Sally Shrapnel, Samuel Hinton, Simon Forsyth, Rex Parsons, John Laffey, Eddy Fan, Robert Bartlett,Daniel Brodie, Aidan Burrell, Davide Chiumello, Alyaa Elhazmi, Giacomo Grasselli, Carol Hodgson, Shingo Ichiba, Carlos Luna, Eva Marwali, Laura Merson, Srinivas Murthy, Alistair Nichol, Mauro Panigada, Paolo Pelosi, Antonio Torres, Pauline Y Ng, Mark Ogino, John Fraser, on behalf of the COVID-19 Critical Care Consortium

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An appraisal of respiratory system compliance in mechanically ventilated covid-19 patients

Gianluigi Li Bassi, Jacky Y Suen, Heidi Dalton, Nicole White, Sally Shrapnel, Jonathon P Fanning, Benoit Liquet, Samuel Hinton, Aapeli Vuorinen, Gareth Booth, Jonathan E Millar, Simon Forsyth, Mauro Panigada, John Laffey, Daniel Brodie, Eddy Fan, Antoni Torres, Davide Chiumello, Amanda Corley, Alyaa Elhazmi, Carol Hodgson, Shingo Ichiba, Carlos Luna, Srinivas Murthy, Alistair Nichol, Pauline Yeung Ng, Mark Ogino, Antonio Pesenti, Huynh Trung Trieu, John Fraser, COVID-19 Critical Care Consortium

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Neurological Manifestations of Coronavirus Disease 2019: A Comprehensive Review and Meta-Analysis of the First 6 Months of Pandemic Reporting

Samuel F. Huth, Sung-Min Cho, Chiara Robba, David Highton, Denise Battaglini, Judith Bellapart, Jacky Y. Suen, Gianluigi Li Bassi, Fabio Silvio Taccone, Rakesh C. Arora, Glenn Whitman, John Fraser, Jonathon P. Fanning.

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Ethical factors determining ECMO allocation

Dao, B., et al. (2021). "Ethical factors determining ECMO allocation during the COVID-19 pandemic." Bmc Medical Ethics 22(1): 12.

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Featured
Variability of oxygen requirements in critically ill COVID-19 patients

Samuel F Huth, Alexander Rothkopf, Lisa Smith, Nicole White, Gianluigi Li Bassi1, Jacky Y Suen, John F Fraser, COVID-19 Critical Care Consortium

Read More →
Global Effort to Collect Data on Ventilated Patients With COVID-19

As the new chair of the Asia-Pacific Chapter of the Extracorporeal Life Support Organization (ELSO), John Fraser, MBChB, PhD, began talking with the group’s members last November about why influenza affects some people worse than others, so much so that they require extracorporeal membrane oxygenation (ECMO).

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  • How Australian medicos brought the world together to beat a deadly virus

    An informal network of the globe’s most brilliant medical minds helped us understand how to treat critically ill COVID-19 patients.

    Read

  • In the news

    A dedicated team at Brisbane's Prince Charles Hospital has collected COVID health data on critically ill patients across the globe. December 2021.

    Watch

  • What does the Consortium mean to our global community

    Established in 2020, the COVID-19 Critical Care Consortium was created to support ICUs at the coal face of the pandemic. The Australian-led initiative quickly became so much more.

    Watch

  • On the world stage

    The Expo 2020 World Majlis in Dubai brings together thought leaders, visionaries and changemakers to explore the future of faster and safer medical innovations. Prof Fraser joins the panel discussion At the Speed of Life - The Future of Medical Innovation 1 Feb 2022.

    Discover

Other Critical Care Research Group projects

  • ICETLab

    Cardiovascular technologies from idea to implementation.

    Discover

  • STARLab

    Imperative research related to the heart, lungs and ECMO.

    Discover

  • ICU of the Future

    Reshaping the experience of intensive care.

    Discover

  • PRIMELab

    PRIMELab has a multidisciplinary team of intensivists, cardiologists, cardiothoracic surgeons, anaesthetists, pneumologists, nurses, and respiratory therapists.

    Discover

  • The Living Heart Project

    Fixing broken hearts with Hypothermic Ex-Vivo Perfusion (HEVP).

    Discover