Effects of red blood cell transfusion on patients undergoing cardiac surgery in Queensland
A retrospective cohort study
Obonyo NG, Dhanapathy V, White N, Sela DP, Rachakonda RH, Tunbridge M, Sim B, Teo D, Nadeem Z, See Hoe LE, Bassi GL, Fanning JP, Tung JP, Suen JY, Fraser JF J Cardiothorac Surg. DOI 10.1186/s13019-024-02974-7
Background: Packed red blood cell (pRBC) transfusion is a relatively safe and mainstay treatment commonly used in cardiac surgical patients. However, there is limited evidence on clinical effects of transfusing blood nearing end-of shelf life that has undergone biochemical changes during storage.
Objective: To investigate evidence of associations between morbidity/mortality and transfusion of blood near end of shelf-life (> 35 days) in cardiac surgical patients.