A Novel Speckle-Tracking Echocardiographic Parameter Assessing Left Ventricular Loading During VA ECMO in a Pre-clinical Model of Cardiogenic Shock

2023
Written By CCRG

Sato K, Heinsar S, Obonyo N, Wildi K, Liu K, Farah S, Ainola C, Sato N, Ijuin S, Ro SK, Fior G, Gandini L, Bouquet M, Wilson E, Passmore M, Hyslop K, Chan J, Platts D, Scalia G, Suen J, Bassi GL, Fraser J Heart Lung Circul DOI: 10.1016/j.hlc.2023.06.562

Background: Left ventricular (LV) stroke work index (SWI) and cardiac power index (CPI) are considered load-independent parameters and can yield better prognostic values than LV ejection fraction (EF) in cardiogenic shock. However, accurate measurement of these parameters using Pressure-Volume catheters (PVC) is too invasive for routine clinical use. The aim of this study was to investigate whether Pressure-Strain Product (PSP), a novel Speckle-Tracking echocardiography (STE) parameter, can non-invasively predict PVC-based LV SWI and CPI in an ovine model of cardiogenic shock undergoing peripheral VA ECMO.

CCRG
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