Follow-up echocardiographic changes in children and youth aged <25 years with latent rheumatic heart disease
Carl J. Francia, John F. Fraser, Robert Justo, Joan Cassimatis, Sophie Manoy and Leanne M. Johnston DOI https://doi.org/10.1016/j.ijcard.2024.131911
Objectives
To estimate progression, regression and persistence rates for borderline and mild-definite latent RHD in children and youth diagnosed at age < 25 years.
Methods
A review was conducted in accordance with Preferred Reporting Items for Systematic reviews and Meta-Analysis guidelines. Electronic databases were searched for latent RHD echocardiography follow-up studies which used World Heart Federation diagnostic criteria. A meta-analysis of outcomes was conducted for borderline and mild-definite disease subcategories.