Follow-up echocardiographic changes in children and youth aged <25 years with latent rheumatic heart disease

Carl J. Francia, John F. Fraser, Robert Justo, Joan Cassimatis, Sophie Manoy and Leanne M. Johnston DOI https://doi.org/10.1016/j.ijcard.2024.131911

Objectives

To estimate progression, regression and persistence rates for borderline and mild-definite latent RHD in children and youth diagnosed at age < 25 years.

Methods

A review was conducted in accordance with Preferred Reporting Items for Systematic reviews and Meta-Analysis guidelines. Electronic databases were searched for latent RHD echocardiography follow-up studies which used World Heart Federation diagnostic criteria. A meta-analysis of outcomes was conducted for borderline and mild-definite disease subcategories.

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