Estimation of Left Ventricular Stroke Work for Rotary Left Ventricular Assist Devices

EL Wu, M Maw, AF Stephens, MC Stevens, Michael, JF Fraser, G Tansley, F Moscato, SD Gregory ASAIO J DOI 10.1097/MAT.0000000000001972

Abstract: Continuous monitoring of left ventricular stroke work (LVSW) may improve the medical management of patients with rotary left ventricular assist devices (LVAD). However, implantable pressure–volume sensors are limited by measurement drift and hemocompatibility. Instead, estimator algorithms derived from rotary LVAD signals may be a suitable alternative. An LVSW estimator algorithm was developed and evaluated in a range of in vitro and ex vivo cardiovascular conditions during full assist (closed aortic valve [AoV]) and partial assist (opening AoV) mode.