In Vitro Hemocompatibility Evaluation of Modified Rotary Left to Right Ventricular Assist Devices in Pulmonary Flow Conditions
Chan, Chris Hoi Houng; Nandakumar, Deepika; Balletti, Nicoletta; Horobin, Jarod; Wu, Eric Lee-Jan; Bouquet, Mahe; Stephens, Andrew; Pauls, Jo P.; Tansley, Geoff; Fraser, John F; Simmonds, Michael J; Gregory, Shaun D. ASAIO Journal DOI 10.1097/MAT.0000000000001049
Background: Right ventricular failure is a common postoperative complication following left ventricular assist device (LVAD) implantation. Left ventricular assist devices are adapted for right ventricular assist device (RVAD) support by reducing the right pump speed or restricting the diameter of the outflow graft by “banding.” We sought to conduct in vitro hemocompatibility testing in a pulmonary flow condition for current modification of an LVAD for RVAD support, with a specific aim to provide benchmark values for future RVAD development.