Predictors of Intensive Care Admission in Hypoxemic Bronchiolitis Infants, Secondary Analysis of a Randomized Trial

D Franklin, FE Babl, J Neutze, S Craig, E Oakley, J Furyk, CM Frampton, N Hasan, TM Pham, L Miller, JF Fraser, SR Dalziel & A Schibler. Journal of Pediatrics DOI: 10.1016/j.jpeds.2022.12.006

Objectives: To evaluate in a pre-planned secondary analysis of our parent randomized controlled trial predictors of intensive care admission in infants with bronchiolitis and analyze if these predictors are equally robust for children receiving high-flow or standard-oxygen.

Study design: A secondary analysis of a multi-center, randomized trial of infants aged <12 months with bronchiolitis and an oxygen requirement was performed using admission and outcome data of all 1472 enrolled infants. The primary outcome was intensive care admission. The predictors evaluated were baseline characteristics including physiological data and medical history.